Immunocytochemical localization of antigens recognized by asymptomatic microfilaremic patient's antisera in microfilariae of Wuchereria bancrofti.
Identifieur interne : 009A24 ( Main/Exploration ); précédent : 009A23; suivant : 009A25Immunocytochemical localization of antigens recognized by asymptomatic microfilaremic patient's antisera in microfilariae of Wuchereria bancrofti.
Auteurs : L C Alves [Brésil] ; F A Brayner ; L F Silva ; J. Miranda ; A. Rocha ; C A PeixotoSource :
- Parasitology research [ 0932-0113 ] ; 2001.
Descripteurs français
- KwdFr :
- MESH :
- analyse : Antigènes d'helminthe.
- croissance et développement : Wuchereria bancrofti.
- immunologie : Anticorps antihelminthe, Filariose lymphatique, Microfilaria, Wuchereria bancrofti.
- Animaux, Humains, Immunohistochimie.
English descriptors
- KwdEn :
- MESH :
- chemical , analysis : Antigens, Helminth.
- chemical , immunology : Antibodies, Helminth.
- growth & development : Wuchereria bancrofti.
- immunology : Elephantiasis, Filarial, Microfilariae, Wuchereria bancrofti.
- Animals, Humans, Immunohistochemistry.
Abstract
Ultrathin sections of microfilariae of Wuchereria bancrofti embedded in hydrophilic resin were incubated with sera from patients, using antisera from asymptomatic microfilaremic patients with different microfilarial densities [1-100 microfilariae (mf)/ml, 101-500 mf/ml, > 1,000 mf/ml]. All groups studied showed reactivity against relevant epitopes in all tissues of microfilariae of W. bancrofti, instead of being localized in a specific nematode region, although the number of colloidal per square micron was inversely proportional to the microfilaremia. Such results confirm data obtained by other authors and indicate a possible role for the humoral response in the mechanism for the destruction of circulating microfilariae.
PubMed: 11763438
Affiliations:
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Miranda</name></author><author><name sortKey="Rocha, A" sort="Rocha, A" uniqKey="Rocha A" first="A" last="Rocha">A. 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Miranda</name></author><author><name sortKey="Rocha, A" sort="Rocha, A" uniqKey="Rocha A" first="A" last="Rocha">A. Rocha</name></author><author><name sortKey="Peixoto, C A" sort="Peixoto, C A" uniqKey="Peixoto C" first="C A" last="Peixoto">C A Peixoto</name></author></analytic><series><title level="j">Parasitology research</title><idno type="ISSN">0932-0113</idno><imprint><date when="2001" type="published">2001</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antibodies, Helminth (immunology)</term><term>Antigens, Helminth (analysis)</term><term>Elephantiasis, Filarial (immunology)</term><term>Humans</term><term>Immunohistochemistry</term><term>Microfilariae (immunology)</term><term>Wuchereria bancrofti (growth & development)</term><term>Wuchereria bancrofti (immunology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Anticorps antihelminthe (immunologie)</term><term>Antigènes d'helminthe (analyse)</term><term>Filariose lymphatique (immunologie)</term><term>Humains</term><term>Immunohistochimie</term><term>Microfilaria (immunologie)</term><term>Wuchereria bancrofti (croissance et développement)</term><term>Wuchereria bancrofti (immunologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Antigens, Helminth</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Antibodies, Helminth</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Antigènes d'helminthe</term></keywords><keywords scheme="MESH" qualifier="croissance et développement" xml:lang="fr"><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="growth & development" xml:lang="en"><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Anticorps antihelminthe</term><term>Filariose lymphatique</term><term>Microfilaria</term><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Microfilariae</term><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Humans</term><term>Immunohistochemistry</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Humains</term><term>Immunohistochimie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Ultrathin sections of microfilariae of Wuchereria bancrofti embedded in hydrophilic resin were incubated with sera from patients, using antisera from asymptomatic microfilaremic patients with different microfilarial densities [1-100 microfilariae (mf)/ml, 101-500 mf/ml, > 1,000 mf/ml]. All groups studied showed reactivity against relevant epitopes in all tissues of microfilariae of W. bancrofti, instead of being localized in a specific nematode region, although the number of colloidal per square micron was inversely proportional to the microfilaremia. Such results confirm data obtained by other authors and indicate a possible role for the humoral response in the mechanism for the destruction of circulating microfilariae.</div></front></TEI><affiliations><list><country><li>Brésil</li></country></list><tree><noCountry><name sortKey="Brayner, F A" sort="Brayner, F A" uniqKey="Brayner F" first="F A" last="Brayner">F A Brayner</name><name sortKey="Miranda, J" sort="Miranda, J" uniqKey="Miranda J" first="J" last="Miranda">J. Miranda</name><name sortKey="Peixoto, C A" sort="Peixoto, C A" uniqKey="Peixoto C" first="C A" last="Peixoto">C A Peixoto</name><name sortKey="Rocha, A" sort="Rocha, A" uniqKey="Rocha A" first="A" last="Rocha">A. Rocha</name><name sortKey="Silva, L F" sort="Silva, L F" uniqKey="Silva L" first="L F" last="Silva">L F Silva</name></noCountry><country name="Brésil"><noRegion><name sortKey="Alves, L C" sort="Alves, L C" uniqKey="Alves L" first="L C" last="Alves">L C Alves</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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